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Roeder, Erhard
- Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia
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Authors
Affiliations
1 Pharmazeutisches Institut der Universitaet, An der Immenburg 4, D-53121 Bonn, DE
2 Institute of Chemistry and Chemical Technology, Mongolian Academy of Science, Ulaanbaatar-51, MN
1 Pharmazeutisches Institut der Universitaet, An der Immenburg 4, D-53121 Bonn, DE
2 Institute of Chemistry and Chemical Technology, Mongolian Academy of Science, Ulaanbaatar-51, MN
Source
Scientia Pharmaceutica, Vol 68, No 2 (2000), Pagination: 207-211Abstract
We isolated four Pyrrolizidine Alkaloids (PA) from Senecio nemorensis L. growing in Mongolia. Their structures were elucidated by spectroscopic methods to be 7-Senecioyl-9-sarracinoyl-retronecine, Retroisosenine, Doriasenine and Bulgarsenine. The alkaloidal pattern is very similar to that of the European Senecio nemorensis L., ssp. nemorensis (Rchb.) Celak. The medicinal use of this plant or of preparations from it may be hazardous to human health because of the high PA level in the plant (≈ 0.1%) and the fact that three of the PA are known to have toxic side-effects.Keywords
Senecio nemorensis; Mongolia; Pyrrolizidine Alkaloids; 7-Senecioyl-9-Sarracinoyl-retronecine; Retroisosenine; Doriasenine; Bulgarsenine.
References
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- Pyrrolizidine Alkaloide in Petasites fragrans
Abstract Views :440 |
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Authors
Affiliations
1 Pharmazeutisches Institut der Universitaet, An der Immenburg 4, D-53121 Bonn, DE
1 Pharmazeutisches Institut der Universitaet, An der Immenburg 4, D-53121 Bonn, DE
Source
Scientia Pharmaceutica, Vol 70, No 4 (2002), Pagination: 407-411Abstract
Three pyrrolizidine alkaloids, senkirkine, petasinine and 7-angeloylretronecine or anisomer have been isolated from Petasites fragrans. Their structures were elucidated by spectroscopic methods.Keywords
Petasites fragrans; Pyrrolizidine Alkaloids; Senkirkine; Petasinine; 7-Angeloylretronecine or Isomer.References
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